Mass Spectrometry Basics by Christopher G. Herbert, R. A. W. Johnstone (CRC Press) Provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. Serves as a refresher for practicing mass spectroscopists by clarifying principles to afford a better appreciation and application of this technology.
Mass Spectrometry Basics describes processes,
applications, and the underlying science in a concise manner supported by
figures and graphics to further comprehension. The text provides practical
approaches to interpreting mass spectral data and step-by-step guides for
identifying chemically relevant compounds. Additionally, the authors have
included an extensive reference section and a quick guide to each chapter that
offers immediate access to key information. This unique reference makes some of
the esoteric aspects of this important area of analysis more readily
comprehensible to those who deal with analytical instruments but who have not
been trained in mass spectrometry. It also serves as a refresher for practicing
mass spectroscopists by clarifying principles to afford a better appreciation
and application of this technology.
Contents: Chemical Ionisation (CI); Laser Desorption Ionisation (LDI); Electron Ionisation (EI); Fast Atom Bombardment (FAB) and Liquid Phase Secondary Ion Mass Spectrometry (LSIMS) Ionisation; Field Ionisation (FI) and Field Desorption (FD); Coronas, Plasmas and Arcs; Thermal Ionisation (TI; Surface Emission of Ions); Electrospray Ionisation (ES); Atmospheric Pressure Ionisation (API); Z-Spray Combined Inlet/Ion Source; Thermospray and Plasmaspray Interface; Particle-Beam Interface; Dynamic Fast Atom Bombardment and Liquid (phase) Secondary Ion Mass Spectrometry (FAB/LSIMS) Interface; Plasma Torches; Sample Inlets for Plasma Torches. Part A: Gases; Sample Inlets for Plasma Torches. Part B: Liquid Inlets; Sample Inlets for Plasma Torches. Part C: Solid Inlets; Lasers and Other Light Sources; Nebulisers; Hybrid Orthogonal Time-of-Flight (oa-TOF) Instruments; Hybrid Magnetic Sector Time-of-Flight (TOF) Instruments; Hybrid Hexapole Time-of-Flight (TOF) Instruments; Hybrid Quadrupole Time-of-Flight (TOF) Instruments; Ion Optics of Magnetic/Electric Sector Mass Spectrometers; Quadrupole Ion Optics; Time-of-Flight (TOF) Ion Optics; Orthogonal Time of Flight (oa-TOF) Ion Optics; Point Ion Collectors (Detectors); Array Collectors (Detectors); Comparison of Multipoint Collectors (Detectors) of Ions; Time-to-Digital Converters; Origin and Uses of Metastable Ions; Linked Scanning and Metastable Ions in Quadrupole Mass Spectrometry; Linked Scanning and Metastable Ions in Magnetic Sector Mass Spectrometry; Gas Chromatography (GC) and Liquid Chromatography (LC); Gas Chromatography / Mass Spectrometry (GC/MS); Liquid Chromatography / Mass Spectrometry (LC/MS); High Resolution Accurate Mass Measurement: Element Compositions; Choice of Mass Spectrometer; Analysis of Peptides and Proteins by Mass Spectrometry
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