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Review Essays of Academic, Professional & Technical Books in the Humanities & Sciences



Clinical Malignant Hematology by Mikkael A. Sekeres, Matt Kalacyio, Brian Bolwell (McGraw-Hill Just the Facts: McGraw-Hill Professional) The only comprehensive guide to the clinical management of hematologic and lymphatic cancers.
Filling an unmet need in the clinical literature, this commanding, just-in-time reference sheds light on the full spectrum of cancers in the blood, bone marrow, and lymphatic system (leukemia, lymphoma, myeloma). Clinical Malignant Hematology is edited by staff members from the renowned Taussig Cancer Center at the Cleveland Clinic, which has pioneered some of the most important clinical discoveries and treatment trends in recent years.
Present is a consistent, unified patient management strategy in each chapter, as well as a streamlined three-section format that expertly examines ontogeny and physiology of blood cells, myeloid neoplasia, and lymphoid neoplasia. There is also never-before-published perspectives and precise recommendations for dosing and other critical areas that reflect the latest scholarship of this increasingly vital field.


  • Full coverage of all treatment modalities-chemotherapy, monoclonal antibodies, and hematopoietic stem cell transplantation
  • Strong background chapters that offer guidance on how to address treatment complications and other supportive care issues
  • A detailed, regimen-based orientation in each chapter
  • Abundance of clinical pictures and photomicrographs displaying examples of peripheral blood smears and bone marrow aspirates
  • Uniform headings and tables in each chapter, which convey specific recommendations on the work-up, staging, diagnosis, differential diagnosis, and treatment of hematologic malignancies
  • Nearly 200 illustrations 

The clinical aspects of hematologic malignancies have changed dramatically over the past decade. The development of targeted therapies, based on years of advanced understanding of basic scientific mechanisms of disease, has led to their widespread use and ultimately to the first decrease in cancer-related mortality not attributable to screening programs. The impact of these advances will be fully felt over the next two decades, when the population of older adults in the United States is expected to double, and continued evolution of intensive therapy and supportive mea­sures will make approaches such as bone marrow transplantation available to more patients than ever before.

Resources available to clinical oncologists or hema­tologists who treat patients with hematologic malignancies are limited. With this in mind, we planned a textbook devoted solely to this topic. Recognizing, also, that oncologists and hematologists are busier than ever and require accessible information about specific topics, we asked our authors to write focused chapters that address different aspects of a disease, and that would be useful to both general and disease-specific practicing oncologists and hematologists, physicians-in-training, researchers, and nurses. We are proud of the end-product.

Sections of Clinical Malignant Hematology are divided by disease, and each disease is further divided into specialty areas where applicable. These areas include epidemiology, risk factors, and classification; molecular biology, pathology, and cytogenetics; clinical features and making the diagnosis; treatment approach to all disease subtypes; and treatment of relapsed or refractory disease, including new frontiers in therapy. In addition, we have included chapters about specialty topics within hematologic malignan­cies, both within disease sections and in the last part of the book. These topics range from disease-specific indications for bone marrow transplantation and management of infections to treatment of the pregnant patient with a hematologic malignancy and fertility issues in this patient population.

Chapter authors are world experts in their fields. We asked them to use evidence-based findings in the presentation of their material but not at the expense of offering practical information about managing these complicated and often very sick patients. We are grate­ful to our authors for rising to this challenge and helping us to produce the first definitive textbook on hematologic malignancies.


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